D-penicillamine-induced glomerulonephritis with crescent formation: Remission following drug discontinuation
نویسندگان
چکیده
منابع مشابه
Antiglomerular basement membrane glomerulonephritis following D-penicillamine-associated nephrotic syndrome.
Antiglomerular basement membrane (anti-GBM) glomerulonephritis (GN) is rare and is characterized by rapidly progressive GN with IgG linear deposits along the GBM in immunofluorescence study and circulating anti-GBM antibodies. This form of GN usually occurs without previous renal disease, but some cases of membranous GN have been reported with secondary development of antiGBM disease [1,2]. Adm...
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Dear Editor, Wilson’s disease (WD) is a rare autosomal recessive disorder of copper homeostasis with a prevalence of 30 affected individuals per million population. Treatment is based on oral chelating agents such as D-penicillamine. Despite its effectiveness, Dpenicillamine presents significant adverse effects. Among them is proteinuria and nephrotic syndrome. An 11 yearold boy was admitted wi...
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Idiopathic membranous glomerulonephropathy is a well defined clinical and pathological entity (Cluck et al, 1973). It is postulated to be an immune-complex disease. There seems to be some variation in the life expectancy in this group of patients, nonetheless most agree that slow progression to renal failure is usual. Evolution of membranous nephropathy to a rapidly progressive crescentic glome...
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Myasthenia gravis is a disorder of impaired neuromuscular transmission resulting in weakness and abnormal fatigability on exertion, improved by anti-acetyl cholinesterase drugs. A number of drugs are known to exacerbate myasthenia gravis or interfere with neuromuscular transmission. We report a case of D-penicillamine induced myasthenia gravis who developed ptosis, diplopia and easy fatigabilit...
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Rheumatoid arthritis can be a very mutilating disease and, as a result, the likelihood of patients with rheumatoid arthritis requiring surgery and anaesthesia is increased. D-penicillamine (D-Pen) has been used in the treatment of rheumatoid arthritis and Wilson's disease since the early 1960s. Its true mode of action is unknown, but it appears to modify the immune response. Treatment with D-Pe...
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ژورنال
عنوان ژورنال: Indian Journal of Nephrology
سال: 2013
ISSN: 0971-4065
DOI: 10.4103/0971-4065.111862